IP-GeoScape® Library

The IP-GeoScape® Library (IPGL) offers a large range of IP-GeoScape visual landscapes of the molecular IP space associated with a biological target area of interest. Each IP-GeoScape reveals the multi-dimensional relationship between molecules within the target area of interest to guide strategic decision-making across R&D, patenting and licensing.

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IP-GeoScape® Library Targets


Currently Available:

  • Adenosine A2a receptor antagonist
  • Beta lactamase inhibitor
  • CFTR modulator
  • CXCR3 chemokine antagonist
  • Epidermal growth factor receptor antagonist
  • Estrogen receptor alpha antagonist
  • Farnesoid X receptor agonist
  • FGF4 receptor antagonist
  • Hepatitis C virus NS3 protease inhibitor
  • Hepatitis C virus NS5B polymerase inhibitor
  • Histone deacetylase-6 inhibitor
  • HIV protease inhibitor
  • Indoleamine pyrrole 2 3-dioxygenase 1 inhibitor
  • IRAK-4 protein kinase inhibitor
  • Jak1 tyrosine kinase inhibitor
  • Jak2 tyrosine kinase inhibitor
  • Jak3 tyrosine kinase inhibitor
  • Mcl-1 differentiation protein inhibitor
  • MEKK-5 protein kinase inhibitor
  • Programmed cell death protein 1 inhibitor
  • Protein arginine N-methyltransferase 5 inhibitor
  • Retinoid Z receptor gamma antagonist
  • TLR-7 agonist
  • TLR7 antagonist
  • Urate anion exchanger 1 inhibitor

Coming Soon:

  • Axl tyrosine kinase receptor inhibitor
  • Bcl-2 protein inhibitor
  • Cyclin-dependent kinase-4 inhibitor
  • Cyclin-dependent kinase-6 inhibitor
  • DNA gyrase inhibitor
  • EP4 prostanoid receptor antagonist
  • Estrogen receptor antagonist
  • FGF1 receptor antagonist
  • Flt3 tyrosine kinase inhibitor
  • K-Ras GTPase inhibitor
  • Muscarinic M4 receptor agonist
  • NMDA receptor antagonist
  • Opioid receptor kappa agonist
  • Opioid receptor mu agonist
  • Phosphoinositide-3 kinase beta inhibitor
  • Poly ADP ribose polymerase 1 inhibitor
  • Proteasome inhibitor
  • Protein tyrosine phosphatase-1B inhibitor
  • Ret tyrosine kinase receptor inhibitor
  • Rho associated protein kinase 2 inhibitor
  • RIP-1 kinase inhibitor
  • STAT-3 inhibitor
  • Stimulator of interferon genes protein stimulator
  • Tryptophan 2,3 dioxygenase inhibitor
  • Tubulin receptor antagonist

FAQs


The landscape tab does not have axes, instead the relative distance of one molecule to another is used to indicate relative molecular structural similarity. Similar molecules are clustered together, and similar clusters are close to each other. Therefore, the more similar a molecule is to another the closer they appear on the landscape, with very different molecules positioned far apart.
All IP-GeoScapes contain exemplified molecules from the relevant patents. We specifically include only exemplified molecules because, while the complete genus could be enumerated and mapped, our analysis has shown that the results are unwieldy and no more useful than exemplified only. The exemplified molecules are a representative sample of the genus and will, ultimately, delimit the granted claims.
While we strive for 100% of all exemplified molecules for the relevant patents, some structures are unextractable. However, we always ensure that a sufficient percentage of the exemplified molecules for the relevant patents are featured so users are able to gain the key intelligence they need to do their work.
Of course! We are adding new IP-GeoScapes associated with new biological targets all the time, but we always welcome suggestions as to new targets to focus on. So if we don’t list something you’re interested in, get in touch and we will work with you to get it added as soon as possible.
IP-GeoScape is designed for the way medicinal chemists think and work, facilitating more efficient and effective new molecule discovery. The Landscape tab reveals areas not currently being explored through analysis of, and substructure searching within, the occupied and unoccupied IP space, whilst also showing how molecular IP associated with a target has developed over time, and where competitors are currently active.

The MedChem tab provides a view intended to be specifically useful for molecular design. It provides a simplified, tiled representation of the molecular IP landscape arranged by structural similarity. Each tile, when selected, gives a simple, but powerful, representation of the contents of the cluster by displaying an image of the most representative structure from the cluster with the most common substructure within the cluster highlighted. This tiled view clearly reveals the unoccupied space which are ripe for new molecules, and by selecting the tiles surrounding such spaces, users can see how the chemotypes on opposite sides of the unoccupied space can be merged to create new compounds.
IP-GeoScape is designed for the way legal, business development, licensing and/or patent informatics professionals think and work, delivering actionable IP intelligence in a uniquely visual way. The Landscape tab enables users to see and understand the competitive space associated with a biological target including where competitors are particularly active, and how the molecular IP has developed over time. The Competitive Overview tab then breaks the data down on the basis of who, what, and when- presenting the data by assignee and priority year, revealing at-a-glance which assignees were active when and enabling in depth review of the patents themselves.

The Analysis tab is designed to be primarily used by IP and business development professionals, revealing overlaps in the IP. This overlap information is very useful for IP professionals to scan for potential interference. Not all overlaps mean interference, but they can alert you to the risk. This view is also useful for licensing professionals seeking partnerships or other deals as overlaps in the most recent IP can be indicative of areas of mutual interest. In fact, this precise type of analysis has been successfully used to find both interference and to establish joint ventures in specific areas.